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Updated: Jan 16, 2026

Identifying DNA Mutations in Purified Hematopoietic Stem/Progenitor Cells
11:06

Identifying DNA Mutations in Purified Hematopoietic Stem/Progenitor Cells

Published on: February 24, 2014

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人体突变在DNA不匹配修复基因,突变率和新抗原负载在急性淋巴细胞白血病的体质突变

Diana Karen Mendiola-Soto1,2, Laura Gómez-Romero3,4, Juan Carlos Núñez-Enríquez5

  • 1Laboratorio de Innovación y Medicina de Precisión, Núcleo A, Instituto Nacional de Medicina Genómica, Ciudad de Mexico 14610, Mexico.

Pharmaceuticals (Basel, Switzerland)
|September 27, 2025
PubMed
概括

研究人员在儿科急性淋巴细胞白血病 (ALL) 中确定了潜在的新抗原. 这些发现支持基于新抗原的免疫疗法作为一种有前途的治疗方法,特别是在复发ALL患者中.

关键词:
在HLA-A*02:01中.HLA-B*39:05:05 HLA-B*39:05:05: HLA-B*39:05:05: HLA-B*39:05:05: HLA-B*39:05: HLA-B*39:05: HLA-B*39:05: HLA-B*39:05: HLA-B*39:05: HLA-B*39:05: HLA-B*39:05: HLA-B*39:05: HLA-B*39:05: HLA-B*39:05: HLA-B*39:05: HLA-B*39:05: HLA-B在 HLA-C*07:01 中.急性淋巴细胞白血病急性淋巴细胞白血病外基因组测序是指外基因组的测序.新抗原是一种新抗原.

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