在瑞士发生阿坎萨摩巴角膜炎的发病率
Frank Blaser1, Felix Grimm2, Philipp B Baenninger3
1Department of Ophthalmology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Microorganisms
|September 27, 2025
概括
瑞士的阿坎萨摩巴角膜炎 (AK) 发病率低且稳定,平均每年每百万病例为2.29例. 感染在夏季更为常见,这凸显了预防措施的必要性.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 寄生虫学的寄生虫学
背景情况:
- 全球关于阿坎萨摩巴角膜炎 (AK) 的报道正在增加.
- 瑞士AK的发病率以前没有被确立.
- 阿坎萨摩巴角膜炎是一种严重的眼睛感染,可能导致视力丧失.
研究的目的:
- 为了确定瑞士Acanthamoeba角膜炎的全国发病率.
- 在14年的时间内分析AK病例的趋势和季节性变化.
主要方法:
- 从2010年1月到2023年12月进行的回顾性多中心研究.
- 包括所有来自瑞士眼科医院的PCR和/或培养阳性阿坎萨摩巴菌的结果.
- 根据联邦统计局的人口数据计算发病率.
主要成果:
- 在14年的时间里,确定了271例阿坎塔梅巴病毒阳性病例.
- 年平均发病率为每百万人口2.29例.
- 夏季观察到更高的发病率 (32.1%),随着时间的推移没有显著变化 (p=0.47).
结论:
- 瑞士的AK发病率低但稳定,与其他工业化国家相比,瑞士的AK发病率低但稳定.
- 季节性变化表明环境暴露会影响感染率.
- 预防措施至关重要,尤其是在温暖的月份.
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