与登革热相关的眼部并发症:频谱,诊断和管理
Jiaxin Deng1, Yaru Zou1, Mingming Yang1
1Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo 113-8510, Japan.
Pathogens (Basel, Switzerland)
|September 27, 2025
概括
登革热病毒感染可以导致严重的眼睛问题,如出血和炎症,影响视力. 早期识别和治疗对于管理这些眼部并发症至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 登革热病毒感染通常会影响眼睛,出现出血,脑膜炎和视网膜血管变化.
- 眼部表现可以发生在急性发烧阶段或几周后,高达25%的住院患者出现眼部症状.
- 登革热感染与患上新发卵膜炎病例的风险增加有关.
研究的目的:
- 审查目前对登革热相关眼睛疾病的理解.
- 为了强调眼部参与登革热的各种临床表现.
- 突出早期诊断和管理登革热相关的眼部并发症的重要性.
主要方法:
- 文献综述整合了关于登革热眼表现的当前知识.
- 对诊断方法的分析,包括临床检查,成像 (OCT,血管造影) 和实验室确认.
- 对前部和后部眼部部位卷入的治疗策略的评估.
主要成果:
- 由免疫机制驱动的血眼屏障的破坏导致血管泄漏,组织损伤和缺血.
- 诊断包括临床评估,成像和登革热确认.
- 治疗方法从局部类固醇治疗轻度前部炎症到全身性皮质类固醇和免疫调节剂治疗严重的后部疾病.
结论:
- 视觉结果取决于眼部干扰的严重程度; 前部卵膜炎通常会在没有持久影响的情况下消失,而后部部位疾病可能会导致永久的视力缺陷.
- 早期识别和适当管理对于优化眼部并发症登革热患者的视觉结果至关重要.
- 需要进一步研究针对性,基于机制的疗法,以提高登革热相关眼睛疾病的治疗疗效.
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