当地卫生部门COVID-19疫苗接种工作和相关结果:肯塔基州杰斐逊县的证据
Shaminul H Shakib1, Seyed M Karimi1, J Daniel McGeeney2
1Department of Health Management and Systems Sciences, School of Public Health and Information Sciences, University of Louisville, Louisville, KY 40202, USA.
Vaccines
|September 27, 2025
概括
当地的COVID-19疫苗计划减少了病例,住院和死亡,特别是在白人居民中. 公平的疫苗接种运动对于解决健康结果的种族差异至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 健康 公平 卫生 公平
背景情况:
- 在COVID-19疫苗接种中的差异已被记录.
- 有限的研究存在于当地疫苗计划对COVID-19结果的影响.
- 这项研究研究了疫苗计划对病例,住院和死亡的影响.
研究的目的:
- 评估由路易斯维尔地铁公共卫生和健康部 (LMPHW) 协调的COVID-19疫苗剂量的影响.
- 为了评估这些对COVID-19结果的影响,在肯塔基州杰斐逊县的邮政编码中按种族划分.
- 分析2020年12月至2022年5月的数据.
主要方法:
- 使用固定效应的纵向模型,将邮政编码作为生态时间序列单位.
- 测量了疫苗剂量与COVID-19结果之间的关联,时间差异不同 (1周至1个月).
- 对时间及其与邮政编码的相互作用进行调整的模型.
主要成果:
- 在1周的滞后时间内,在LMPHW疫苗剂量和COVID-19结果之间发现了显著的负相关性 (11.6个较少的病例,0.4个较少的住院,每100剂量减少0.3个死亡).
- 疫苗剂量始终与白人居民的死亡率降低相关 (每100剂量0.2例死亡).
- 在黑人居民中没有观察到任何显著的关联;然而,时间趋势显示在高峰疫苗注射期间的结果下降.
结论:
- 及时接种COVID-19疫苗对于减轻严重后果至关重要,特别是在新变种的情况下.
- 疫苗结果协会的种族差异凸显了公平,社区驱动的疫苗倡议的需要.
- 这些活动可能会改善整体人口健康状况.
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