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COVID-19疫苗:过敏患者接种疫苗的耐受性

Natalie Kogseder¹, Viktoria Puxkandl^1,2, Wolfram Hötzenecker^1,2,3

¹Department for Dermatology and Venerology, Kepler University Hospital, 4020 Linz, Austria.

|September 27, 2025

概括

对于过敏和先前过敏症患者来说,COVID-19疫苗接种是安全的. 抗组胺前期治疗可能会减少副作用,但先前对疫苗的过敏反应需要谨慎.

科学领域:

免疫学免疫学免疫学
过敏和免疫学过敏和免疫学
疫苗学疫苗学疫苗学

背景情况:

COVID-19疫苗引入了不确定性和犹,特别是在害怕过敏反应的过敏患者中.
接受过敏特异性免疫疗法 (SIT) 的患者被评估了他们对COVID-19疫苗的反应.
由于对该群体疫苗安全性的担忧,需要在现实世界中收集数据.

研究的目的:

评估COVID-19疫苗在接受SIT的显著过敏患者的安全性和不良反应.
在这个特定的患者群体中确定不良反应的危险因素和保护措施.

主要方法:

在SIT上对57名过敏患者的图表审查,包括并发症,IgE,三酶和HADS得分.
对COVID-19疫苗接种情况和报告的不良事件的问卷分析.
评估过去的过敏反应和前期药物使用情况.

主要成果:

93%的患者接种了COVID-19疫苗,57%的人报告了不良反应,大多数是非特异性 (一般疾病症状).
一个1级过敏反应记录在一个患者之前的疫苗反应和高的疫苗接种前焦虑.
抗组胺前期治疗与较少的非特异性疫苗接种后反应相关.

结论:

对于具有严重过敏和过敏过敏史的人来说,COVID-19疫苗似乎是安全的.
以前对疫苗接种过敏反应可能表明COVID-19疫苗反应的风险更高.
抗组胺前期治疗可以减轻过敏患者的副作用;建议进行进一步的前性研究.

关键词:

在 COVID-19 疫情中,哈德斯 (HADS) 已经有了过敏是一种过敏.抗胺剂是一种抗胺剂.疫苗疫苗疫苗疫苗

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