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Updated: Jan 16, 2026

In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox
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Published on: August 28, 2019

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对量化结构-活性关系 (QSAR) 模型的审查,以预测由化学物质引起的甲状腺激素系统干扰

Marco Evangelista1,2, Ester Papa1

  • 1QSAR Research Unit in Environmental Chemistry and Ecotoxicology, Department of Theoretical and Applied Sciences, University of Insubria, Via J.H. Dunant 3, 21100 Varese, Italy.

Toxics
|September 27, 2025
PubMed
概括

破坏甲状腺激素 (TH) 系统的化学物质是对发展的关注. 本综述绘制了定量结构-活性关系 (QSAR) 模型,作为动物试验的替代方案,用于预测TH中断风险.

关键词:
在 AOP AOP 中.这就是MIE.在QSAR中使用QSAR.适用性领域 (applicability domain) 是一个应用领域.内分泌干扰 干扰内分泌系统机械主义的解释.分子描述器 分子描述器新方法方法论新方法方法论甲状腺激素系统的破坏 甲状腺激素系统的破坏

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