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纳米乳液和微乳液用于鼻内药物输送:图书统计分析和新兴趋势 (2004-2024)

Ariane Krause Padilha Lorenzett¹, Vanderlei Aparecido de Lima², Clovis Orlando Pereira da Fonseca³

¹Laboratory of Nanostructured Formulations, Universidade Estadual do Centro-Oeste, Alameda Élio Antonio Dalla Vecchia St., 838, Guarapuava 85040-167, PR, Brazil.

|September 27, 2025

概括

鼻内纳米乳液显示出越来越多的潜力,可以将药物输送到大脑,绕过血脑屏障. 本文献分析突出了研究的主要趋势和中枢神经系统疾病的治疗应用.

科学领域:

制药科学制药科学
神经科学是一个神经科学.
图书统计学图书统计学

背景情况:

纳米乳液和微乳液增强药物的溶解性,稳定性和生物可用性.
这些系统对于治疗中枢神经系统 (CNS) 疾病特别有前途.
鼻内注射提供了一种非侵入性的药物输送至大脑的途径.

研究的目的:

进行对有关鼻内纳米乳液的科学出版物的文献计量分析.
确定该领域的出版趋势,主要贡献者和主题集群.
从2004年到2024年绘制中枢神经系统药物输送的鼻内纳米乳液的研究格局.

主要方法:

从Scopus数据库 (2004-2024) 中分析了379篇文章.
使用了Bibliometrix和VOSviewer软件进行圣经识别分析.
审查了出版趋势,国家/机构贡献,期刊影响和关键词同时出现网络.

主要成果:

在过去十年中,印度,美国和中国是领先的国家,观察到大量的出版物增长.
关键的研究主题包括"向大脑"",药物输送"和"鼻内注射".
库尔库明,奎尔丁,卡巴马西平,西巴姆和胰岛素是经常研究的神经退行性和精神疾病的化合物.

结论:

鼻内纳米和微乳液是中枢神经系统非侵入性药物输送的快速增长领域.
进一步的研究应侧重于弥合翻译差距,以提高有效性,安全性和监管合规性.
这一分析提供了有价值的概述,以指导未来的创新,用于脑疾病的鼻内输送平台.

关键词:

图书馆计量标准 (Bibliometrix) 是一个这是一种鼻腔内科的治疗方法.这是一种微乳液微乳液.这是一种纳米乳液纳米乳液.这是科学测量科学.

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