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开发比卡胺即时释放剂量形式的体外-体外相关性与双相体外溶解试验

Nihal Tugce Ozaksun1, Tuba Incecayir1

  • 1Department of Pharmaceutical Technology, Faculty of Pharmacy, Gazi University, Etiler, 06330 Ankara, Turkey.

Pharmaceutics
|September 27, 2025
PubMed
概括

双相溶解测试有效地预测药物吸收,为双胺 (BIC) 立即释放片建立了强烈的体外-体内相关性. 这种方法有助于开发难溶性药物的仿制版本.

关键词:
比卡卢胺胺的使用方法在体外溶解的双相 in vitro 溶解.在体外体内相关性 (IVIVC)

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