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Updated: Jan 16, 2026

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在开发Pro-PROTAC用于选择性蛋白质降解的最新进展

Fady Hakem1, Ahmad Abdelwaly2, Reem Alshaman3

  • 1Biomedical Sciences Program, University of Science and Technology, Zewail City of Science and Technology, Giza 12587, Egypt.

Pharmaceutics
|September 27, 2025
PubMed
概括

PROTACs降解目标蛋白质,但面临的交付挑战. 本综述探讨了PROTAC前期药物和支持PROTAC的策略,以提高针对性交付和作用持续时间,以改善临床益处.

关键词:
这就是PROTAC.降解降解降解降解降解降解.在opto-PROTACs中使用.蛋白质酶体蛋白质组是什么泰利多胺的使用方法在任何地方都是无处不在的.

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