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Updated: Jan 16, 2026

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APOBEC3B通过激活PKR/eIF2和AMPD2失调促进SARS-CoV-2的发生

Benjamin Fixman1, Lavanya Manjunath2, Philip Sell3

  • 1Molecular and Computational Biology, Department of Biological Sciences, University of Southern, Los Angeles, CA 90089, USA.

Viruses
|September 27, 2025
PubMed
概括

APOBEC3B (A3B) 蛋白质通过影响细胞翻译和免疫反应来促进SARS-CoV-2感染. 在严重的COVID-19患者中降低A3B水平可能会恢复正常的细胞功能.

关键词:
在 AMPD2 的基础上,AMPD2在APOBEC3B (A3B) 中.基因变换器的基因变换器通过PKR介导的综合应激反应.暂时的作用 临时的作用在SARS-CoV-2的感染性.免疫监管网络是免疫监管网络.发生严重的COVID-19

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