狗和猫的腹膜瘤之后死亡率的预后因素:多变量后勤回归和机器学习方法
Irin Kwananocha1, Sirirat Niyom2, Pharkpoom Budsayaplakorn3
1Center for Veterinary Research and Innovation, Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand.
Veterinary sciences
|September 27, 2025
概括
慢性隔膜 (DH) 和血尿素 (BUN) 的升高显著增加了手术后狗和猫的死亡风险. 这些因素是兽医患者生存结果的关键预测因素.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 外科手术的结果
- 预测因素分析预测因素分析
背景情况:
- 隔膜 (DH) 是狗和猫的严重病症,需要进行手术修复.
- 鉴定瘤后死亡率的预后因素对于改善患者的治疗结果至关重要.
- 传统的统计方法和机器学习为分析复杂的临床数据提供了互补的方法.
研究的目的:
- 为了调查与犬和猫在隔膜漏之后的死亡率相关的预后因素.
- 为了比较多变量逻辑回归和随机森林算法在预测生存的有效性.
- 确定影响腹膜的兽医患者死亡风险的关键临床变量.
主要方法:
- 对接受隔膜流术的狗和猫进行了回顾性分析.
- 应用多变量逻辑回归和随机森林算法来识别预后因素.
- 评估人口和临床变量,包括的慢性和血尿素 (BUN) 水平.
主要成果:
- 总体生存率为78.8%;猫的生存率为77%,狗的生存率为82.5%.
- 慢性腹膜 (DH) (OR=4.01) 和升高的BUN (OR=3.24) 是增加死亡率的显著预测因素.
- 随机森林分析确定的持续时间和BUN作为最关键的预后指标,加强了后勤回归的发现.
结论:
- 慢性DH和升高的BUN是隔膜流后狗和猫死亡的重要危险因素.
- 后勤回归和随机森林算法都有效地确定了关键的预后因素.
- 这些发现为DH患者的风险评估和临床管理提供了宝贵的见解.
相关概念视频
02:43Mouse Models of Cancer Study
Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
02:43Mouse Models of Cancer Study
Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
01:21Cancer Survival Analysis
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...