禁食时间对老年患者在未安静结肠镜检查期间腺瘤检测率的影响:一项回顾性多中心研究
Fu-Qiang Liu1,2, Ying-Hao He1, Han Yan3
1Department of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Chongqing, 400016, Yuzhong District, China.
BMC gastroenterology
|September 27, 2025
概括
对于老年患者的非静止结肠镜,超过8分钟的抽出时间显著增加了腺瘤检测率 (ADR). 这一发现对于优化这一群体的癌症查至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 在瘤学瘤学.
背景情况:
- 结肠镜抽取时间是腺瘤检测率 (ADR) 的关键因素.
- 目前的指导方针建议至少需要6分钟的吸血时间.
- 对于老年患者的非静止结肠镜检查的最佳停药时间尚不清楚.
研究的目的:
- 分析老年患者未化结肠镜检查中禁用时间和ADR之间的关系.
- 为了确定在这个人口群体中最大化ADR的最佳戒断时间.
- 为了比较抽出时间>8分钟与≤8分钟的ADR.
主要方法:
- 在老年患者中进行了1119次无化结肠镜的回顾性多中心研究.
- 分析1分钟的抽出时间及其与ADR的相关性.
- 多变量线性回归以确定影响ADR的因素.
主要成果:
- 最高的ADR (67.02%) 和腺癌检测率 (17.02%) 是在8分钟的停药时间观察到的.
- 戒断时间>8分钟与显著更高的不良反应相关 (OR,1.63;95% CI,1.28-2.06;P < 0.001).
- 在研究中,平均戒断时间为9分钟 (IQR,7-13).
结论:
- 对于优化老年患者非镇静结肠镜检查的ADR来说,至少8分钟的禁用时间至关重要.
- 这一发现特别适用于老年患者,对镇静有禁忌.
- 优化戒断时间可以提高结直肠癌查效率.
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