西班牙的糖尿病和侵入性肺炎球菌病:一项回顾性研究
Enrique Gea-Izquierdo1,2,3, Rossana Ruiz-Urbaez4, Valentín Hernández-Barrera5
1Faculty of Medicine, Pontifical Catholic University of Ecuador, Quito, Ecuador. enriquegea@yahoo.es.
BMC infectious diseases
|September 27, 2025
概括
糖尿病 (DM) 增加了侵入性肺炎球菌疾病 (IPD) 的风险. 1型糖尿病患者面临更高的IPD住院风险,特别是伴随疾病,影响西班牙卫生系统.
科学领域:
- 传染性疾病 传染性疾病
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 糖尿病 (DM) 是一种普遍存在的全球疾病,也是侵入性肺炎球菌病 (IPD) 的已知危险因素.
- IPD是一种严重的感染,由Streptococcus pneumoniae (SP) 引起.
- 这项研究调查了西班牙患有DM的患者的IPD,考虑并发症和其他感染,如流感,COVID-19和RSV.
研究的目的:
- 分析西班牙糖尿病患者入院的侵入性肺炎球菌病 (IPD) 的发生率和危险因素.
- 评估DM,并发症和IPD住院治疗之间的关联.
- 评估流感,COVID-19和RSV对DM患者IPD风险的影响.
主要方法:
- 来自西班牙最低基本数据集 (1997-2022) 的医院出院报告的回顾性分析.
- 包括1型和2型糖尿病患者.
- 使用学生的t测试,奇方测试和逻辑回归来确定IPD的风险因素和几率比率的统计分析.
主要成果:
- 确定了超过1290万名患有DM的患者;3.43%患有1型DM,96.57%患有2型DM.
- 感染Streptococcus pneumoniae的发病率在1型糖尿病患者中为0.50%,2型糖尿病患者中为0.66%.
- 1型糖尿病患者的IPD住院风险显著增加,特别是伴随疾病,而与流感,COVID-19和RSV相关的风险较低.
结论:
- 糖尿病和并发症是导致侵入性肺炎球菌病 (IPD) 的重要因素.
- 这些发现凸显了IPD对西班牙医疗保健系统中DM患者的重大影响.
- 进一步的研究和预防策略是有必要的,以减轻糖尿病人群中的IPD风险.
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