皮毛甲状腺癌中的心理痛苦和睡眠:一个病例对照研究
Mi Zou1, Wenji Liu2, Chen Feng1
1The Second Clinical Medical College, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
BMC psychiatry
|September 27, 2025
概括
乳头甲状腺癌 (PTC) 患者的焦虑,抑郁和睡眠障碍率较高. 轻度睡眠障碍与PTC有关,突出显示了心理健康问题.
科学领域:
- 在瘤学瘤学.
- 精神病学是一个精神病学.
- 睡眠医学 睡眠医学
背景情况:
- 乳头甲状腺癌 (PTC) 是最常见的甲状腺癌,全球发病率不断增加.
- 心理因素越来越多地被认为是PTC病变的潜在贡献者.
- 了解PTC中心理困扰和睡眠障碍的流行程度至关重要.
研究的目的:
- 在PTC患者中调查心理困扰的流行情况,包括焦虑和抑郁症状.
- 评估在被诊断为PTC的个体中睡眠障碍的患病率.
- 检查心理困扰,睡眠障碍和PTC之间的相互关系.
主要方法:
- 一项倾向得分匹配 (PSM) 病例对照研究,将446名PTC患者与匹配的对照进行比较.
- 使用自我评价焦虑量表 (SAS) 和自我评价抑郁量表 (SDS) 评估心理痛苦.
- 使用匹兹堡睡眠质量指数 (PSQI) 和多变量逻辑回归分析评估睡眠质量.
主要成果:
- 在PTC患者中,焦虑障碍 (9.6%对7.0%),抑郁症状 (39.9%对30.0%) 和睡眠障碍 (52.2%对39.0%) 的患病率较高.
- 轻度睡眠障碍与PTC状态有显著的相关性 (OR = 1.694,p < 0.001).
- PTC患者报告睡眠质量较差,包括白天功能障碍和睡眠延迟增加.
结论:
- 心理相关疾病,睡眠功能障碍和PTC诊断之间存在显著的关联.
- 轻度睡眠障碍特别与PTC有关,这强调了心理健康在甲状腺癌中的作用.
- 将心理健康和睡眠评估整合到临床方案中可能会改善PTC患者的治疗结果.
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