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Updated: Jan 16, 2026

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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通过结合Mccc1和Pcca来调节BCAA降解,LncBADR促进了T细胞介导的自身免疫

Yanting Lei1, Jing Yu1, Xinrui Huo2

  • 1Department of Neurobiology, Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, School of Basic Medical Sciences, Harbin Medical University, Harbin, Heilongjiang, 150081, China.

Journal of neuroinflammation
|September 27, 2025
PubMed
概括

长非编码RNA BADR (lncBADR) 通过控制分支链氨基酸 (BCAA) 代谢来调节T细胞功能. 抑制IncBADR通过减少BCAA积累和T细胞炎症来改善自身免疫性疾病.

关键词:
在BCAA降解降解过程中.实验性的自身免疫性脑膜炎.这就是为什么LncBADRR.在T细胞,T细胞.在 mTOR-Stat1 路径上.

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