慢性疼痛和发生性高血压:对400万成年人的观察性研究
Yu Chen1, Fuli Chen1,2, Wenjuan Chen1,2
1Department of Cardiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China.
Journal of health, population, and nutrition
|September 27, 2025
概括
慢性疼痛,特别是在多个部位,显著增加高血压的风险. 即使是局部疼痛,如头痛或背痛,也与更高的血压发生率有关.
科学领域:
- 流行病学 流行病学
- 心血管健康 心血管健康
- 疼痛医学 医学 疼痛医学
背景情况:
- 慢性疼痛和高血压对社会和个人造成重大负担.
- 以前的研究还没有探讨多部位疼痛与高血压风险之间的联系.
研究的目的:
- 研究疼痛部位数量与患高血压的风险之间的关联.
- 为了检查特定类型的疼痛是否与高血压发病率的增加相关.
主要方法:
- 利用了英国生物银行402,230名参与者的数据.
- 分类疼痛部位 (0,1,2,3,≥4,以及"全身疼痛").
- 使用Cox比例危险模型来评估风险,计算危险比率 (HR) 和95%置信区间 (CI).
主要成果:
- 在13.35年的时间里,记录了105,617 (26.3%) 的高血压病例.
- 高血压发生率随着疼痛部位的数量增加而增加,在"全身疼痛"方面达到42.0%.
- 疼痛部位≥3的参与者显示高血压风险显著增加 (HR 1.36-1.62).
- 所有研究的疼痛类型,包括头痛和背痛,都与高血压有关.
结论:
- 疼痛部位的数量被证明与高血压风险增加有关.
- 特定的疼痛状况,如头痛,部/肩部疼痛和背部疼痛,独立地与高血压风险有关.
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