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Updated: Jan 16, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

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测序分析表明,复杂的遗传架构有助于脊柱二叉裂的风险

Madison Strain1, Melanie E Garrett1, Max Bucklan1

  • 1Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina, USA.

Birth defects research
|September 27, 2025
PubMed
概括

这项研究研究了脊柱裂变 (SB) 的遗传风险因素,这是一个常见的神经管缺陷. 研究人员确定了16个关联基因,揭示了对SB的新见解.

关键词:
负载测试 负载测试整个外族群的协会协会.神经管缺陷是一种神经管缺陷.一个单核酸变体.脊椎裂纹 (spina bifida) 是一个传输不平衡测试 传输不平衡测试

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A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations08:22

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

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