晚上更明亮的卧室灯光预测了早期青春期发作的风险:一项为期两年的纵向研究
Yi Zhou1, Wen-Qin Ding1, Ying Li1
1Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China; MOE Key Laboratory of Population Health Across Life Cycle, Hefei, Anhui, China; Anhui Provincial Key Laboratory of Environment and Population Health across the Life Course, Anhui Medical University, Anhui, China.
暴露在夜间的光线 (LAN) 加快了儿童青春期的开始. 较高的LAN暴露,特别是睡前照明,与男孩和女孩的早期青春期发育有关.
科学领域:
- 内分泌学 在内分泌学.
- 环境健康 环境健康
- 儿科 儿科 儿科
背景情况:
- 夜间的光线 (LAN) 是一种环境内分泌干扰物,有可能加速性腺发育.
- 有限的人类证据存在关于LAN对青春期时间的影响.
研究的目的:
- 调查个人卧室LAN暴露与儿童加快青春期发育之间的关联.
- 分析LAN时间,强度和持续时间与早期青春期之间的关系.
主要方法:
- 在中国对886名儿童 (男孩和女孩,年龄在6-10岁) 的前性研究.
- 卧室的LAN曝光用便携式照度计在两个晚上测量.
- 青春期的发展 (女孩的乳腺发育,男孩的丸体积) 用加速失效时间 (AFT) 模型在2年内进行评估.
主要成果:
- 暴露在LAN中的儿童的青春期较早3.84个月 (男孩) 和4.12个月 (女孩).
- 增加LAN持续时间 (≥3 lx) 与早期丸发育 (男孩) 和larche (女孩) 的更高风险相关.
- 睡前照明暴露显示,与醒前照明相比,更明显的加速青春期的风险更大.
结论:
- 个人层面的LAN暴露显著加快了两性青春期的开始.
- 睡前照明对青春期早期发育特别有影响.
- 这些发现突显了环境光线在人类发育中的内分泌干扰作用.
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