对复发性急性鼻炎患者的性别差异分析
Melissa Cummins1, John Dewey2, Nader Ghassan Zalaquett3
1West Virginia School of Osteopathic Medicine, Lewisburg, West Virginia, USA.
The Laryngoscope
|September 27, 2025
概括
患有复发性急性鼻炎 (RARS) 的女性经历了更大的生活质量负担. 这项研究发现,女性患者报告了更糟糕的鼻腔结果,即使在手术后.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 生活质量研究 研究 生命质量研究
- 医学社会学 医学社会学
背景情况:
- 以前的研究表明,患有慢性鼻炎 (CRS) 的女性患者报告生活质量下降.
- 在复发性急性鼻炎 (RARS) 中,性别对 QoL 的影响需要进一步研究.
研究的目的:
- 在被诊断为RARS的患者中调查性别特异性 QoL 的差异.
- 为了比较男性和女性RARS患者之间的主观疾病负担.
主要方法:
- 一项回顾性队列研究分析了来自耳鼻喉科诊所的RARS患者.
- 审查了客观的鼻炎证据 (CT/内镜) 和患者的并发症.
- 鼻腔结局测试-22 (SNOT-22) 用于评估基线和手术后的QoL差异.
主要成果:
- 包括116名RARS患者 (65.5%为女性);在CT或内镜分数中没有发现性别之间的显著差异.
- 女性患者报告了显著较差的SNOT-22基线得分 (p=0.001) 和更高的自身免疫性疾病,头痛和焦虑的患病率.
- 手术后,SNOT-22分数在两种性别都显著改善,但仍然与女性性别独立相关 (coeff. 8.4,95% CI 2.2-14.7) 发现了这一点.
结论:
- 与男性相比,患有RARS的女性患者的主观疾病负担更高.
- 在RARS患者中,性别是较差QOL的独立预测因素.
- 需要进一步的研究,以了解导致这些性别差异的潜在生物学和心理社会因素.
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