[在雄激素替代疗法和治疗阴性双胞胎症的联合疗法后恢复射精质量]
E R Rozhivanova1, R V Rozhivanov1, E N Andreeva2
1I.I. Dedov Endocrinology Research Centre.
概括
与丸激素和人类胆管性淋巴激素 (hCG) 的联合治疗改善了精子度,比单独使用丸激素替代疗法更有效. 然而,这两种治疗都没有显著改善精子的运动性或形态.
科学领域:
- 内分泌学 在内分泌学.
- 生殖医学 生殖医学
- 男人的健康 男人的健康
背景情况:
- 男性的阴性双胞胎症需要优化雄激素替代疗法 (ART) 来增强生殖潜力.
- 目前的ART策略旨在改善阴道下男性的生育结果.
研究的目的:
- 为了比较和人类胆性淋巴激素 (hCG) 组合疗法 (ART/hCG) 与单独替代疗法 (ART) 在恢复射精质量的有效性.
- 为了评估不同治疗方法对阴茎男性精子参数的影响.
主要方法:
- 一项前性观察性研究包括53名患有阴性腺的男性,他们接受了ART (n=19) 或ART/hCG (n=34) 治疗超过5年.
- 评估了射精参数,包括精子度,运动性和形态学.
- 统计学显著性是使用p值<0.05.5来确定的.
主要成果:
- 精子度在ART组显示出显著的负面趋势,而在ART/hCG组没有观察到显著的变化.
- 在两组之间发现了精子度变化的显著差异.
- 两组均表现出精子运动性和形态学的显著负面动态,治疗组之间没有显著差异.
结论:
- 与和hCG结合疗法在恢复精子度方面表现出优异的结果,与单独的替代疗法相比.
- 两种治疗方法都没有为改善精子运动性和形态学带来令人满意的结果.
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