一个研究框架,以支持重新参与和持续参与艾滋病毒护理
Marie-Claude C Lavoie1, Elvin H Geng2
1Center for International Health, Education, and Biosecurity, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
The lancet. HIV
|September 27, 2025
概括
优化艾滋病毒护理连续性至关重要,因为许多被诊断出艾滋病毒的患者会脱离治疗. 让他们重新参与治疗可以改善个体健康,减少社区传播,这需要全球研究议程.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 尽管在实现联合国艾滋病规划署95-95-95目标方面取得了进展,但艾滋病毒管理的一个重大挑战是保持护理的连续性.
- 在全球范围内,87%的艾滋病毒感染者 (PLWH) 在2024年知道自己的身份,其中94%的接受治疗的人实现了病毒抑制.
- 然而,高达40-50%的被诊断出艾滋病毒的个体从艾滋病毒治疗中脱离,冒着不良健康结果和传播的风险.
研究的目的:
- 突出优化护理连续性和重新参与因艾滋病毒护理而失去的个人的关键需求.
- 强调在脱离和重新参与中细微的概念区别的重要性.
- 倡导制定全球研究议程和为有效的重新参与战略提供方法指导.
主要方法:
- 这一观点综合了当前关于艾滋病毒护理脱离和重新参与的数据和研究差距.
- 它强调需要方法学的进步,以更好地理解和解决这些问题.
- 作者呼吁统一数据收集,同时为证据生成和协作提供灵活性.
主要成果:
- 许多被诊断为艾滋病毒感染者被排除在护理之外,这影响了个人健康和公共卫生工作.
- 停止艾滋病毒治疗会增加病毒载量,死亡风险和艾滋病毒的进一步传播.
- 目前关于持续保留和重新参与的研究很少,方法上的局限性阻碍了进展.
结论:
- 有效的重新参与策略对于改善个人健康结果和减少艾滋病毒传播至关重要.
- 全球研究议程和方法指导对于协调和有意的方法来重新参与艾滋病毒护理至关重要.
- 需要更清晰的脱离和重新参与的概念框架,以促进研究和干预开发.
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