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Updated: Jul 30, 2026

Single Synapse Indicators of Glutamate Release and Uptake in Acute Brain Slices from Normal and Huntington Mice
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具有致病性KCNQ2变异的人类iPSC衍生的谷氨酸性神经元表现出过度活跃的爆发表型

Maria Sundberg1, Carole Shum2, Erika M Norabuena3

  • 1Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Neurobiology of disease
|September 27, 2025
PubMed
概括

致病性KCNQ2基因变异会导致严重的神经疾病. 来自患者的神经元显示出明显的细胞和网络功能障碍,为向药物查和治疗开发提供了新的途径.

关键词:
是一种病.神经发育障碍 神经发育障碍通道中的.干细胞是一种干细胞.

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