在轻微缺血性中风中持续存在的视力缺陷
Humza Qureshi1, Raj G Saraiya1, Manisha Koneru2
1Cooper Medical School of Rowan University, Camden, NJ, USA.
概括
患有持续视力缺陷 (PeVD) 的轻度缺血性中风 (MIS) 患者的中风严重程度较高,但90天的功能结果没有恶化. 需要进一步的研究来探索在MIS中对PeVD的替代结果措施.
科学领域:
- 神经学 神经学
- 脑卒中医学 脑卒中医学
- 临床结果研究研究
背景情况:
- 与严重中风相比,轻度缺血性中风 (MIS) 的结果是不太了解的.
- 在MIS中预测长期结果的预测器需要进一步研究.
- 持续视力缺陷 (PeVD) 对MIS功能障碍的影响还没有得到充分的描述.
研究的目的:
- 为了比较MIS患者与没有PeVD的功能结果.
- 评估MIS后PeVD和长期功能残疾之间的关联.
主要方法:
- 成年急性缺血性中风患者的回顾性单中心队列研究 (2019-2023年).
- 根据国家卫生研究院中风量表 (NIHSS) 定义的MIS,入院时的得分≤5和24小时.
- 24小时以非零视野NIHSS子评分定义的PeVD;主要结果是90天修改的兰金尺度 (mRS).
主要成果:
- 在1041名MIS患者中,有10.4%患有PeVD.
- 患有PeVD的患者具有更高的呈现和24小时NIHSS得分.
- PeVD与更高的90天死亡率和mRS得分有关,但多变量分析表明24小时NIHSS,而不是PeVD,预测了更糟糕的功能结果.
结论:
- 少数MIS患者经历了PeVD.
- PeVD与中风的严重程度有关,但与90天的功能结果无关.
- 对于患有PeVD的MIS患者,应探索超越mRS的替代功能结果措施.
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