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Updated: Jan 6, 2026

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
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在粘膜皮肤屏障中平衡IL-17介导的保护和IFN-γ驱动的病理

Lucas Dos Santos Dias1, Michail S Lionakis1

  • 1Fungal Pathogenesis Section, Laboratory of Clinical Immunology & Microbiology (LCIM), National Institute of Allergy & Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.

Trends in immunology
|September 27, 2025
PubMed
概括

互白素-17 (IL-17) 维持屏障完整性,而过度的干扰素- (IFN-γ) 可能会损害它,导致粘膜皮肤感染. 这表明免疫病理,而不仅仅是免疫缺陷,导致屏障感染.

关键词:
在APECED中,您可以使用APECED.在IFN-γ中使用IFN.它们的IL-17是IL-17.抗微生物类的抗微生物.屏障的完整性 屏障的完整性候选症候群病是一种候选症.表面上皮质的破坏破坏.免疫病理学 免疫病理学粘膜皮肤表面的表面.

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