在口腔生物膜中,木炭和化物牙膏的抗菌作用
Ashley N Bowers1, Caroline Coradi Tonon1, Sam Yeo2
1American Dental Association, Science & Research Institute, Chicago, IL, USA.
Archives of oral biology
|September 28, 2025
概括
牙膏中的化物的类型比木炭更重要,用于对抗细菌和预防. 化 (NaF) 显示出最佳的抗菌作用,而化 (SnF2) 的效果最低.
科学领域:
- 口腔微生物学 口腔微生物学
- 牙科材料科学 牙科材料科学
背景情况:
- 木炭牙膏在美白方面很受欢迎,但它们的抗菌作用尚未得到充分证实.
- 关于木炭与含有各种化物化合物的非木炭牙膏的抗菌功效的比较数据有限.
研究的目的:
- 为了比较木炭牙膏与含有化 (NaF),化 (SnF2) 或单化 (NaMFP) 的非木炭牙膏的抗菌疗效.
- 评估木炭添加剂对化牙膏对口腔生物膜的抗菌活性的影响.
主要方法:
- 多种多种口腔生物膜 (Streptococcus mutans,S. gordonii,S. sanguinis) 在酸盘上进行培养.
- 生物膜被用木炭和非木炭牙膏泥,盐水或化 (CHX) 处理了60秒.
- 使用每毫升殖民地形成单位 (CFU/mL) 和定量聚合酶链反应 (qPCR) 来量化抗菌效应.
主要成果:
- 化 (NaF) 牙膏表现出最高的抗菌活性 (46.8%的减少),其次是单化 (NaMFP) (34.9%).
- 化 (SnF2) 的有效性很小 (≤5.7%).
- 添加木炭并没有增强抗菌效果,并且稍微降低了NaF的性能;化物类型是有效性的主要决定因素.
结论:
- 化物类型显著影响抗菌功效,NaF是最有效的,SnF2是最不有效的.
- 木炭添加剂没有明显的抗菌益处,可能会轻微降低NaF的性能.
- 选择合适的化物化合物对预防空比使用木炭更为关键.
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