在COVID-19后的时期,儿科乳腺炎的持续增加:基于国家数据的9年间断时间序列分析
Apolline Furgier1, Romain Basmaci2, Zaba Valtuille3
1Paris Cité University, Infection, Antimicrobials, Modelling, Evolution (IAME) Research Unit, Paris, France; Department of General Pediatrics, Pediatric Infectious Disease and Internal Medicine, Robert Debré University Hospital, Assistance Publique - Hôpitaux de Paris, Paris Cité Université, Paris, France.
The Journal of pediatrics
|September 28, 2025
概括
COVID-19非药物干预 (NPI) 最初减少了儿科乳腺炎病例,但导致了大流行后的显著反弹. 这项研究强调了NPI对儿童感染和病原体转移的持久影响.
科学领域:
- 儿童传染病 儿童传染病
- 流行病学 流行病学
- 公共卫生干预措施 公共卫生干预措施
背景情况:
- 由于COVID-19的流行,需要广泛的非药物干预措施 (NPI).
- 这些NPI对儿科乳腺炎及其致病原体发生率的影响仍在调查中.
- 了解这些影响对于管理未来的公共卫生危机至关重要.
研究的目的:
- 评估COVID-19流行病相关的NPI对儿科乳腺炎发病率的影响.
- 为了确定NPI实施和取消后的致病原体和并发症的变化.
- 在流行病期间和之后为管理儿科感染的策略提供信息.
主要方法:
- 使用法国国家监测数据 (2016-2024) 进行了基于人口的中断时间序列分析.
- 在儿童 (<18岁) 中住院的乳腺炎病例被分析为每月发病率趋势.
- 准松回归模型考虑了季节性来评估NPI影响.
主要成果:
- 总共包括了7390例儿科乳腺炎病例.
- 在严格的NPI期间,乳腺炎发病率下降了58.9%,随后在NPI后相比预期趋势增加了71.7%.
- 在NPI后观察到由Streptococcus pyogenes (+627.8%) 和Streptococcus pneumoniae (+135.6%) 引起的乳腺炎的显著增加. 并发症和手术的发生率保持稳定.
结论:
- 儿童乳腺炎发病率和病因改变的持续增加发生在COVID-19大流行后.
- 这些变化与NPI的实施和随后的解除有关.
- 这些发现强调了在未来的公共卫生管理中需要考虑与流行病相关的后果.
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