过氧化蒸发对抗抗甲素的有效性金黄色葡萄球菌,扩展光谱β-乳糖酶产生细菌,以及Clostridioides difficile
Narimi Miyazaki1, Ai Kurumiya1, Mina Takayama1
1Department of Infection Prevention and Control, Aichi Medical University Hospital, Aichi, Japan.
概括
过氧化蒸发有效地杀死表面的耐药细菌和Clostridioides difficile子. 这种无触摸方法为医疗机构的环境消毒提供了一个有希望的解决方案,以减少感染.
科学领域:
- 环境微生物学环境微生物学
- 感染控制的方法是感染控制.
- 消毒技术 消毒技术 消毒技术
背景情况:
- 医疗相关感染 (HAI) 由于环境受到耐药细菌和子形成生物体 (如Clostridioides difficile) 的污染而带来风险.
- 手动消毒方法是标准的,但容易出现人为错误,可能会留下残留的病原体.
研究的目的:
- 评估过氧化蒸发对关键医疗保健相关病原体的杀菌和杀菌效果.
- 在模拟的医院环境中评估一个紧型过氧化蒸发装置 (NOCOSPRAY2) 的有效性.
主要方法:
- 使用NOCOSPRAY2模拟医院病房消毒,使用不同的喷雾时间和接触时间.
- 表面接种耐甲基金色葡萄球菌 (MRSA),产生ESBL的大肠杆菌和Clostridioides difficile子.
- 确定存活的细菌和子数量蒸发后的日志减少值.
主要成果:
- 在6分钟蒸发后对MRSA显著的杀菌作用 (≥5日志).
- 在蒸发2分钟后,对产生ESBL的大肠杆菌有显著的杀菌作用 (≥5日志).
- 蒸发2分钟后对C. difficile产生显著的杀菌效应 (≥3个日志);安全的过氧化水平保持.
结论:
- 过氧化蒸发显示了对抗性细菌和C. difficile子的广泛疗效.
- 这种无触摸消毒方法在高触摸表面是有效的.
- 它是手工清洁的宝贵补充或替代品,用于医疗机构的环境净化.
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