甲状腺眼病中的纤维带:导致持续的术后限制的一个因素
Veronika Yehezkeli1, Stacy L Pineles1, Federico G Velez1
1Stein Eye Institute, Department of Ophthalmology University of California, Los Angeles, David Geffen School of Medicine at UCLA, Los Angeles, California.
概括
眼睛中的无症状纤维带可以在甲状腺眼病 (TED) 中引起限制性偏. 通过手术去除这些带,改善了两名TED患者的眼睛运动和手术结果.
科学领域:
- 眼科医生 眼科 眼科
- 轨道解剖学 轨道解剖学
- 这是一种眼 (Strabismus).
背景情况:
- 附加的眼外纤维带是轨道结构.
- 这些带通常是无症状的,但在先天性头骨缩性神经障碍中可能具有症状.
- 它们在获得性偏中扮演的角色,特别是在甲状腺眼病 (TED) 等炎症性疾病中,是未被认可的.
研究的目的:
- 调查甲状腺眼病 (TED) 中无症状辅助眼外纤维带的临床意义.
- 探索这些带在导致持续限制性偏的潜在作用.
- 评估纤维带切除对TED患者手术结果的影响.
主要方法:
- 两名患有甲状腺眼病 (TED) 和限制性偏的患者的病例报告.
- 评估包括轨道成像和强制导管测试 (FDT).
- 手术干预涉及眼手术,在手术期间识别和切除纤维带.
主要成果:
- 两位患者都出现了限制性偏和积极的强迫导管测试 (FDT),尽管肌肉脱落.
- 在手术内发现的纤维带的切除正常化FDT.
- 这种干预导致了手术结果的改善和运动问题的解决.
结论:
- 无症状的辅助眼外纤维带可以在TED的进展中变得具有临床意义.
- 在TED中,这些带可能会导致非典型的运动模式和持续的限制性视.
- 在精选的TED案例中,纤维化带的识别和切除对于成功的眼手术至关重要.
相关概念视频
Hyperthyroidism I: Introduction
29
Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
29
Hyperthyroidism II: Pathophysiology
26
Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH...
26
Graves' Disease I: Introduction
22
Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence...
22
Graves Disease II: Pathophysiology
26
Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor,...
26
Hypothyroidism II: Pathophysiology
23
Hypothyroidism is a disorder characterized by insufficient production of thyroid hormones, which regulate metabolism, energy balance, and multiple organ systems.TypesHypothyroidism is classified based on the level of dysfunction. Primary hypothyroidism results from intrinsic thyroid gland dysfunction, causing reduced hormone production despite normal or increased stimulation. Secondary hypothyroidism arises from inadequate thyroid-stimulating hormone (TSH) secretion by the pituitary. Tertiary...
23


