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在双特异抗体生物类似物中通过组合调节器调节N-糖化

Xu Shengnan1, Wang Pan1, Wang Xiaofei1

  • 1Nanjing Chia Tai-Tianqing Pharmaceutical Co Ltd, Fanghua Pharmaceutical Research Institute, Department of Biology, Nanjing, 210046, China.

Protein expression and purification
|September 28, 2025
PubMed
概括

在生物类似双特异抗体 (BsAbs) 中优化糖化是相似性的关键. 使用银河糖和三甲氨基甲 (Tris) 有效调节N-甘氨酸,而不会影响细胞生长或纯度.

关键词:
添加剂 添加剂 添加剂生物类药物是生物类药物.细胞培养培养的细胞培养.葡萄糖基酶化是什么? 葡萄糖基酶化单克隆抗体是一种单克隆抗体.

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