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身体质量指数对接受MRI镇静治疗的儿童不良事件的影响
Jaimee S Holbrook1, Jason M Kane1,2, Mei Han3
1Department of Pediatrics, University of Chicago Medicine, Chicago, Illinois.
Hospital pediatrics
|September 28, 2025
概括
接受MRI镇静的身体质量指数 (BMI) 高的儿童面临不良事件和呼吸道干预的风险增加. 体重不足的儿童在这些手术期间也有更高的不良事件风险.
科学领域:
- 儿科麻醉学 儿科麻醉学
- 医疗成像安全 医疗成像安全
- 公共卫生与流行病学
背景情况:
- 超过20%的美国儿童有不健康的体重指数 (BMI).
- 用于磁共振成像 (MRI) 的镇静在儿童中很常见,包括那些有不健康的BMI的儿童.
- 了解儿科镇静期间与BMI相关的风险对于患者的安全至关重要.
研究的目的:
- 确定身体质量指数 (BMI) 类别与接受MRI镇静治疗的儿童的不良事件 (AE) 和呼吸道干预风险之间的关联.
- 量化不同BMI分类的儿童中AEs和气道干预的增加几率.
主要方法:
- 在66个中心对39393名接受MRI镇静治疗的儿童进行了回顾性横截面研究.
- 儿童的BMI值被分为体重不足,健康体重,超重,肥胖和严重肥胖.
- 使用多变量后勤回归来分析与BMI相关的AE和气道干预的风险.
主要成果:
- 被归类为超重,肥胖和严重肥胖的儿童显示,重大和中度AEs的几率显著增加.
- 具体来说,对AEs的调整后赔率比 (aORs) 在这些组的1.58至1.86之间.
- 在超重 (aOR 1.61),肥胖 (aOR 1.83) 和严重肥胖 (aOR 1.9) 的儿童中,也观察到主要气道干预的几率增加.
结论:
- 超重,肥胖和严重肥胖的儿童接受MRI镇静剂的副作用和呼吸道干预的风险明显更高.
- 体重不足的儿童也面临着在MRI镇静期间出现不良事件的风险.
- 这些发现强调了在MRI程序期间考虑BMI在儿童镇静风险评估中的重要性.
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