在精神病学中使用迷幻药辅助治疗的伦理问题:系统的范围审查
Chiara Caporuscio1,2,3, Christopher Poppe1,3, Astrid Gieselmann4
1Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Psychiatry and Neurosciences, Campus Charité Mitte, Berlin, Germany.
Psychological medicine
|September 29, 2025
概括
在精神病学中,使用psilocybin和MDMA等物质的幻觉辅助疗法正在出现. 本次审查确定了关键的伦理考虑,包括安全,同意和访问,以实现负责任的实施.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 医学伦理 医学伦理
- 药理学 药理学是指药理学的学科.
背景情况:
- 迷幻物质 (例如,psilocybin,MDMA) 在临床试验中显示出治疗用途的前景.
- 心理学辅助疗法的整合到精神病学实践中,需要对道德挑战进行彻底的审查.
- 现有的文献需要对道德问题的全面概述,以指导负责任的实施.
研究的目的:
- 进行范围审查,确定和分析与迷幻药辅助治疗相关的伦理问题.
- 提供临床试验和迷幻疗法的应用中的伦理考虑的系统概述.
- 为未来的研究和关于迷幻药辅助治疗的伦理辩论提供信息.
主要方法:
- 在多个数据库 (MEDLINE,PsycInfo,CINAHL,HeinOnline,PsycArticles) 进行系统的文献搜索.
- 包括对人类参与者和精神病患者进行同行评审的研究,讨论在迷幻治疗中的伦理问题.
- 代的诱导和演编码来识别和分类伦理主题.
主要成果:
- 七个主要主题出现了:患者安全和福祉,治疗关系,知情同意,公平和获取,研究伦理,特殊背景和社会/文化影响.
- 该审查综合了与临床试验和更广泛的临床应用相关的伦理考虑.
- 确定的主题突出了迷幻药辅助治疗中道德挑战的复杂性.
结论:
- 这些发现为关于迷幻药辅助治疗的细微道德讨论提供了基础.
- 解决已识别的伦理问题对于安全和公平地整合这些疗法至关重要.
- 需要进一步的研究和对话,以确保心理学辅助疗法的负责任的社会推广.
相关概念视频
Psychosurgery
1.5K
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
1.5K
Hallucinogens and Psychedelics
607
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
607
CNS Stimulants: Psychedelic Agents
693
Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
693
Altered States of Awareness
1.0K
Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
1.0K
Psychosis: Goals of Pharmacotherapy
474
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
474
Drug Therapy
245
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
245


