一项前性的多中心观察性研究,评估猫的急性输血反应的发生率和危险因素
Georgina B F Hall1, Rachael Birkbeck2, Benjamin M Brainard3
1Clinical Science and Services, The Royal Veterinary College, London, UK.
Journal of veterinary internal medicine
|September 29, 2025
概括
猫类输血反应 (TRs) 的发生率使用TRACS定义进行了评估. 发烧性非溶血性TRs是最常见的,与较旧的红细胞 (RBC) 单位和输液使用有关.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 血液学 血液学 血液学
- 关键的护理关键的护理
背景情况:
- 血液产品输血反应 (TRs) 在猫的发生率是高度可变的.
- 需要标准化定义来准确评估猫类患者的TRs.
研究的目的:
- 评估接受猫血制品的猫中急性TRs的发生率和做法.
- 应用输血反应小动物共识声明 (TRACS) 定义进行标准化评估.
主要方法:
- 在美国,英国和澳大利亚的14家转诊医院进行了一项前性的多中心观察研究.
- 在2022年3月至2024年1月期间,收集了444只猫接受608种猫血制品的数据.
- 使用TRACS标准记录了急性TRs.
主要成果:
- 含红细胞产品的急性TRs发生率为7.8%,血产品为1.1%.
- 发烧性非溶血输血反应 (FNHTRs) 是与红细胞产品相关的最常见的TRs (5.7%).
- 红细胞单位年龄的增加和输液的使用 (与注射器驱动器相比) 与FNHTR的更高几率有关.
- 在因怀疑TR而停止的输血中,46.4%不符合TRACS标准.
- 在18.3%的病例中,24小时内死亡,但与TR发展无关.
结论:
- 这项研究报告了基于TRACS指南的猫的输血反应发生率.
- 发烧性非溶血性TRs是猫中最常见的反应类型.
- 红细胞单位年龄和施用方法 (输注) 是与猫的FNHTR相关的重要因素.
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