纤维肌痛在喘中的患病率及其对喘控制的影响:一个病例对照研究
Suat Konuk1, Alp Ozel2, Emine Ozsari1
1Department of Chest Diseases, Bolu Abant Izzet Baysal University, Bolu, Turkey.
Annals of medicine
|September 29, 2025
概括
纤维肌痛在喘患者中很常见,可能会使喘控制恶化. 仅靠喘控制测试 (ACT) 可能无法可靠地检测纤维肌痛,这表明需要更好的评估工具.
科学领域:
- 肺部医学 肺部医学
- 类风湿病学 类风湿病学
- 临床免疫学临床免疫学
背景情况:
- 喘和纤维肌痛是影响生活质量的慢性疾病.
- 这两种情况都有共同的潜在炎症和神经生理机制.
研究的目的:
- 为了确定喘患者纤维肌痛的患病率.
- 为了评估纤维肌痛对喘控制的影响.
主要方法:
- 一项病例控制研究包括120名喘患者和120名对照人群.
- 使用2016年ACR标准 (WPI,SSS) 诊断出纤维肌痛.
- 通过喘控制测试 (ACT) 评估喘控制;统计分析包括t测试,奇方位,后勤回归和ROC分析.
主要成果:
- 在喘患者中,纤维肌痛的患病率为16.7%,对照组为3.3% (p < 0.001).
- 患有纤维肌痛的喘患者的ACT得分较低 (18.2比20.1,p=0.004) 和不受控制的喘率较高 (60%比35%).
- 纤维肌痛与失控喘的几率增加有关 (OR=2.16,p=0.103);ACT显示没有与WPI/SSS的相关性,也没有纤维肌痛的歧视力.
结论:
- 纤维肌痛是喘中经常出现的并发症,可能会损害喘控制.
- 在喘患者中,ACT得分可能不足以确定纤维肌痛.
- 建议在常规喘护理中使用多维评估工具,以识别像纤维肌痛这样的并发症.
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