支气管切除症患者中肺部恶化的频率,持续时间和成本
Maitreyee Mohanty1, Claudia Leiras2, Haiyan Sun2
1Insmed Incorporated, Bridgewater, NJ, USA.
Journal of medical economics
|September 29, 2025
概括
一个基于成本的新算法确定了支气管病变的恶化,揭示了更长的持续时间和更高的医疗保健成本. 这种方法提供了一种新方法来描述行政索赔数据中的恶化情况.
科学领域:
- 肺部医学 肺部医学
- 卫生经济学 卫生经济学
- 数据科学数据科学数据科学
背景情况:
- 行政索赔数据经常使用固定的时间来定义支气管切除症恶化,限制了恶化特征的分析.
- 开发了一种新的基于成本的算法,以更好地描述行政索赔数据中的恶化.
研究的目的:
- 应用一种基于成本的新算法来利用行政索赔数据来描述支气管瘤恶化.
- 将基于成本的算法识别的恶化与传统基于索赔的定义识别的恶化进行比较.
主要方法:
- 一项队列研究使用了Merative MarketScan商业索赔和遭遇数据库 (2016-2022).
- 用基于成本的算法分析了支气管切除症患者 (≥18岁),通过每周全因成本的显著增加来识别恶化.
- 恶化的持续时间是由与基线相比每周成本显著增加的时期定义的.
主要成果:
- 该研究分析了9005名支气管切除症患者,确定了49750例基于成本的恶化.
- 基于成本的恶化平均持续时间为1周,82.8%的患者经历了≥3次恶化.
- 患有基于成本的恶化症的患者与没有成本的患者相比,每年呼吸费用显著增加 (14,116美元) (3,390美元).
结论:
- 算法识别的基于成本的恶化经常持续超过3周.
- 患有基于成本的恶化症的患者承担了更高的医疗保健和呼吸系统费用.
- 这种基于成本的方法在索赔数据中提供了更细致的支气管切除症恶化的特征.
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