"睡觉"的深度大脑刺激,针对本质震中的腹部中间丘脑:系统性审查
Jack Horan1,2, Eoghan Donlon3,4, Richard A Walsh3,4
1Department of Neurosurgery, Beaumont Hospital, Dublin, Ireland.
British journal of neurosurgery
|September 29, 2025
概括
对于基本震 (ET) 的睡眠深度大脑刺激 (DBS) 是一种安全有效的治疗方法. 这种方法的功能结果和并发症率与传统的清醒DBS程序相提并论.
科学领域:
- 神经外科 神经外科
- 神经学 神经学
背景情况:
- 深度大脑刺激 (DBS) 针对腹部中间丘脑 (VIM) 有效地治疗基本震 (ET).
- 传统上,在清醒的患者中,微电极记录 (MER) 证实了位.
- 睡眠DBS,在全身麻醉下利用间接解剖准,已成为另一种选择.
研究的目的:
- 系统地审查睡眠时对基本震的DBS程序的结果.
- 评估VIM针对ET的睡眠DBS的安全性和有效性.
主要方法:
- 根据PRISMA指南进行了系统审查.
- 搜索包括PubMed,Web of Science和Cochrane数据库,寻找与VIM目标在ET中睡眠DBS的研究.
- 分析了9项涉及229名患者 (406人) 的研究数据.
主要成果:
- 功能性改善范围从48%到71% (加权平均值57.62%).
- 实现了亚毫米精度,辐射误差平均为0.83毫米.
- 并发症率与清醒过程相比,加权平均值为7.45%.
结论:
- 针对VIM的睡眠DBS是一种安全有效的治疗基本震的方法.
- 该程序提供了高精度和可与清醒MER引导的DBS相比的结果.
- 需要进一步的随机对照试验来比较睡眠和清醒的DBS.
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