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Updated: Jan 16, 2026

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
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Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients

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使用HPLC同时估计菲内伦和卡纳格利弗洛辛:在代谢稳定性研究中的应用

Shivam Rathaur1, Parag Varshney1, Sachin Vishwakarma1

  • 1Division of Pharmaceutics and Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, India.

Bioanalysis
|September 29, 2025
PubMed
概括

一种新的HPLC方法准确地测量了Finerenone (FNR) 和Canagliflozin (CFZ) 组合在一起. 这种经过验证的技术是敏感的,可靠的,对于药物代谢研究是有用的.

关键词:
在Canagliflozin中使用.没有一个Fineerenone.这是一个HPLC-PDA.肝脏微小体稳定性 肝脏微小体稳定性药品应用 药品应用同时分析方法的同时分析方法.

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Multi-step Preparation Technique to Recover Multiple Metabolite Compound Classes for In-depth and Informative Metabolomic Analysis11:25

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