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脊髓刺激:在脊髓损伤后缓解慢性疼痛的新兴策略

Qiwen Wang1, Ying Zhang1,2, Huifeng Zhang1,2

  • 1Department of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.

Neural regeneration research
|September 29, 2025
PubMed
概括

脊髓刺激 (SCS) 通过调节神经信号和减少炎症,有效地治疗脊髓损伤后的慢性疼痛. 需要进一步的大规模试验来确认长期疗效.

关键词:
有GABA活性的神经元慢性疼痛是一种慢性疼痛.电刺激疗法是一种电刺激疗法.神经再生的神经再生神经炎症性疾病的神经炎症性疾病神经元可塑性 神经元可塑性神经病性疼痛是一种神经性疼痛.神经保护神经保护疼痛管理 疼痛管理脊髓损伤 脊髓损伤 脊髓损伤脊髓刺激 脊髓刺激

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Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
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