评估男性胎儿外部生殖器形态:对超声波技术和规范价值的系统审查
Nikit Venishetty1, Akash Chauhan2, Ishant Goel2
1Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, USA.
概括
阴茎长度,宽度和阴道距离 (AGD) 的胎儿超声波测量缺乏标准化. 这一审查产生了对外部病毒化生殖器发育的规范性生长曲线,突出了对一致协议的需要.
科学领域:
- 产前医学产前医学
- 医疗成像医学成像
- 人类发展 人类发展
背景情况:
- 阴茎长度,宽度和阴道距离 (AGD) 的胎儿超声评估是常见的,但缺乏标准化的测量技术.
- 测量方法的变化可能会影响评估外部病毒化生殖器发育的可靠性.
- 建立规范性数据对于监测典型的胎儿生长和发育至关重要.
研究的目的:
- 系统地审查关于胎儿阴茎长度,宽度和AGD的超声波测量现有文献.
- 评估已发表研究中使用的测量技术的变异性.
- 根据妊娠年龄,为外部病毒化的生殖器发育生成规范性生长曲线.
主要方法:
- 按照PRISMA指南进行了系统审查,搜索了PubMed,谷歌学者和科学网.
- 包括报告胎儿阴茎长度,宽度或按妊娠年龄分类的AGD超声波测量的研究.
- 数据被提取,标准化为平均尺寸和95%置信区间,并导出回归方程.
主要成果:
- 九项研究符合纳入标准,包括关于阴茎长度,宽度和AGD的数据.
- 为阴茎长度 (y=0.7862x - 8.4627),宽度 (y=0.4209x - 3.1445) 和AGD (y=1.0129x - 11.239) 生成了回归方程.
- 质量评估表明,研究参数存在显著偏差风险 (51.97%±21.5%的低风险).
结论:
- 生成的生长曲线为正常的胎儿生殖器发育提供了一个参考.
- 测量技术的显著变化需要制定标准化的评估协议.
- 需要进一步的研究来提高测量的一致性,并评估这些超声波发现在异常发育中的预测价值.
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