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Updated: Jan 16, 2026

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硬度激活的肝星细胞通过TGM2/ITGB1介导的矩阵重塑和线粒体转移促进HCC迁移

Man Wang1, Yannan Xu1, Yongbin Meng1

  • 1The First Affiliated Hospital of Naval Medical University, Shanghai, China.

JHEP reports : innovation in hepatology
|September 29, 2025
PubMed
概括

高肝硬度驱动肝细胞癌 (HCC) 通过肝星细胞 (HSC) 激活的进展. 转胺酶2 (TGM2) 和整体蛋白β1 (ITGB1) 在高细胞中促进HCC复发.

关键词:
在HCC中,HCC是HCC.肝脏的星状细胞是什么矩阵的刚度 矩阵的刚度线粒体转移是指线粒体转移.手术后复发的情况在TGM2/ITGB1中使用.

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