在腹部上部恶性瘤中进行放射治疗的姿势固定技术的比较研究
Ji-Hua Han1, Dong-Cheng He1, Xiao-Ye Zhang1
1Department of Radiation Oncology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, China.
Frontiers in oncology
|September 29, 2025
概括
将热塑性体膜与安全气囊相结合,可显著减少腹部上部瘤的放射治疗设置错误. 这种技术提高了位置精度,降低了随机和系统错误,以获得更好的患者结果.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
- 放射治疗技术 放射治疗技术
背景情况:
- 精确的患者定位在上腹部恶性瘤的放射治疗中至关重要.
- 设置错误可能导致目标体积和周围器官处于危险的低剂量或过量剂量.
- 优化姿势固定技术对于提高治疗精度至关重要.
研究的目的:
- 评估热塑体膜和安全气囊技术相结合的热塑体膜与单独的热塑体膜在减少设置错误方面的有效性.
- 为了比较两种技术之间的随机错误 (Σ),系统错误 (σ) 和规划目标量 (PTV) 利 (MPTV).
- 评估不同姿势固定方法对腹部上部瘤患者的位置精度的影响.
主要方法:
- 一项涉及77名患上腹部上部恶性瘤的患者的比较研究.
- 患者被分为观察组 (热塑性体膜+气囊) 和对照组 (仅限热塑性体膜).
- 沿X,Y和Z轴的设置错误使用圆束计算机断层扫描 (CBCT) 进行测量,并记录在计划CT图像中. 使用威尔科克森等级和值测试进行了统计分析.
主要成果:
- 与对照组相比,观察组在三方向设置错误 (X,Y,Z) 和由此产生的位移向量 (T) 中显示出统计学上显著的减少 (p < 0.05).
- 随机错误 (Σ),系统错误 (σ) 和PTV边际 (MPTV) 在观察组中始终较小.
- 结合技术的结果是改善了位置精度,减少了患者设置的变化.
结论:
- 热塑性体膜和安全气囊的组合是一种优越的姿势固定方法,用于减少腹部上部恶性瘤的放射治疗设置错误.
- 这种技术增强了位置重复性,最大限度地减少了随机和系统错误,并允许较小的PTV边际.
- 实施这种综合方法可以提高治疗效率,并更好地保护瘤邻近的健康组织.
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