慢性失眠的协同针和神经调节:一个结构化的叙事审查,有系统的搜索和未来的方向
Wang Meng1, Wang Mingqiang1, Zhang Junyang2
1Institute of Basic Theory of Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, China.
Frontiers in neurology
|September 29, 2025
概括
失眠影响全球数百万人,影响生活质量. 新兴研究表明,针和神经调节的结合可能提供有效,安全和个性化的失眠治疗.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 综合医学是一个整体的医学.
背景情况:
- 失眠是一个普遍的全球健康问题,影响10-20%的成年人.
- 它与抑郁症和心血管疾病等慢性疾病有关,降低了生活质量,增加了医疗保健成本.
- 目前的治疗方法,包括药物治疗和对失眠的认知行为疗法 (CBT-I),在有效性,安全性或可访问性方面存在局限性.
研究的目的:
- 审查非药物治疗失眠的近期进展.
- 评估针和神经调节技术的潜力,单独和组合.
- 综合这些新兴疗法的有效性和安全性的证据.
主要方法:
- 进行了结构化的叙事审查,对2010年至2025年间发表的研究进行了系统的搜索.
- 包括93项研究进行了定性综合.
- 使用四个定性类别来评估证据确定性:高,中等,低,非常低.
主要成果:
- 针显示了通过自主和神经调节改善睡眠的持续益处和高安全性.
- 像TMS,tDCS和VNS这样的神经调节技术为睡眠障碍提供了快速发病和精确的向.
- 初步证据表明,在将针与神经调节相结合时,可以产生协同效应,从而提高治疗个性化和疗效.
结论:
- 针和神经调节是治疗失眠的有希望的途径,提供了更好的安全性和有效性.
- 结合这些模式可能会带来协同效益,但需要进一步的研究.
- 大规模的多中心随机对照试验对于验证疗效,优化方案和确保综合性失眠疗法的安全至关重要.
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