通过儿童表面呼吸肌EMG评估支气管扩展剂反应
Baiting He1, Feng Li2, Simin Liu1
1State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, People's Republic of China.
Journal of asthma and allergy
|September 29, 2025
概括
呼吸肌电动图 (EMG) 可以有效地区分患有失控喘的儿童和健康的同龄人. 这种方法提供了一个可行的替代品,当螺旋计对儿科喘评估具有挑战性.
科学领域:
- 儿科肺病学 儿科肺病学
- 呼吸系统生理学 呼吸系统生理学
- 生物医学工程 生物医学工程
背景情况:
- 呼吸道可逆性,以强迫呼气体积在第一秒 (FEV1) 支气管扩张后增加≥12%表示,是关键的喘标志物.
- 在儿童中测量FEV1通常是具有挑战性的,因为螺旋测量性能存在困难.
- 需要使用替代方法来评估小儿喘时的支气管扩展剂反应.
研究的目的:
- 评估表面呼吸肌电肌图 (EMG) 在区分患有非控制性喘的儿童与健康对照者的有用性.
- 评估呼吸道肌肉的EMG是否可以作为评估儿童支气管扩展剂反应的可行方法.
主要方法:
- 14名患有非控制性喘的儿童和28名健康儿童参与了这项研究.
- 隔膜电肌图 (EMGdi) 和副侧肋间EMG (EMGpara) 与气流和螺旋计 (FEV1) 在支气管扩展剂服药前后记录在一起.
- 失控的喘是由症状和支气管扩展剂反应来定义的.
主要成果:
- 所有参与者都获得了高质量的EMGdi和EMGpara.
- 在42名儿童中,有18名儿童没有正确进行螺旋计.
- 在喘儿童和健康对照组 (分别p<0.001和p<0.05) 之间观察到支气管扩张后EMGdi和EMGpara变化的显著差异.
- 接收器操作特征分析显示EMGdi (0.995) 的高精度和EMGpara (0.755) 的良好精度在区分组中.
结论:
- 表面呼吸肌EMG是评估儿童支气管扩展剂反应的可行和有效工具.
- 电磁图谱测量可以成功地将患有失控喘的儿童与健康人区分开来,为螺旋计提供了有价值的替代方案.
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