带状鼻:一种不寻常的呈现方式
Abdelnassir Abdelgabar1, Ayesha Farooq1, Quratulain Jabbar1
1General Internal Medicine and Acute Medicine, Diana, Princess of Wales Hospital, Grimsby, GBR.
Cureus
|September 29, 2025
概括
疹病毒 (Varicella zoster virus,简称VZV) 的重新激活可以导致没有带状疹 (zoster sine herpete) 的脑炎. 这一案例突出显示了在免疫能力强的患者中使用PCR和CSF分析诊断VZV脑炎.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 疹病毒 (Varicella zoster virus,简称VZV) 引起水,并在神经元中建立潜伏状态.
- 再激活通常表现为疹 (shingles),通常与疹后神经疼痛.
- 带状疹 (ZSH) 是一种罕见的VZV再激活,没有皮肤病变,使诊断复杂化.
研究的目的:
- 报告一例VZV脑炎的病例,呈现为状疹 (ZSH).
- 强调ZSH的诊断挑战,特别是神经复杂症.
- 为了说明成功的治疗和诊断确认.
主要方法:
- 一个免疫能力强的女性患有雷头痛和困惑的案例报告.
- 通过脑脊液 (CSF) 中的阳性VZV聚合酶链反应 (PCR) 证实了诊断.
- 治疗包括两周的静脉注射阿西克洛维尔.
主要成果:
- 患者表现出神经症状 (头痛,困惑),没有皮肤皮疹.
- 脊髓的分析和PCR证实了VZV感染.
- 在阿西克洛维尔治疗后,脊髓瘤的临床和生物化学参数得到了解决.
结论:
- 状疹 (ZSH) 可以出现严重的神经并发症,如脑炎.
- 早期诊断ZSH相关脑炎至关重要,可以通过PCR实现.
- 用阿西克洛维尔及时治疗导致ZSH脑炎的良好结果.
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