下肢截肢后的死亡率:一项葡萄牙研究
Maria Pires1, João Diniz2, Ana Aguiar3
1Physical Medicine and Rehabilitation, Unidade Local de Saúde do Algarve, Faro, PRT.
Cureus
|September 29, 2025
概括
下肢截肢 (LEA) 具有较高的长期死亡率,但由于更好的心血管护理,生存率可能正在改善. 血管疾病是LEA后不良结果的主要原因和危险因素.
科学领域:
- 整形外科 整形外科 整形外科
- 血管外科 血管外科
- 康复医学 康复医学 康复医学
背景情况:
- 下肢截肢 (LEA) 仍然是一种常见的手术,主要与糖尿病 (DM) 和外周动脉疾病有关.
- 虽然历史上与高死亡率有关,但最近的趋势表明,可能是由于心血管疾病管理的进步,大LEA后的生存率可能有所改善.
研究的目的:
- 量化下肢截肢 (LEA) 后的长期死亡率.
- 评估伴随性疾病对LEA后的总死亡率的贡献.
主要方法:
- 一项回顾性,单中心的观察性研究分析了2015年1月至2024年6月期间接受LEA的730名患者的医疗记录.
- 数据包括患者人口统计,并发症,截肢原因和水平,以及随访期间的死亡率结果.
主要成果:
- 5年和15年的死亡率分别为20%和26%. 主要原因是血管疾病 (64%) 和创伤 (19%).
- 与瘤和血管疾病相关的截肢,关节脱节和关节截肢显示出较差的生存率.
- 糖尿病和高血压被确定为急性后死亡的危险因素.
结论:
- 这项研究证实了LEA后的高长期死亡率,但表明生存率的潜在改善.
- 血管疾病是导致LEA后死亡的主要原因和重要贡献者.
- 预防策略和全面的跨学科护理,包括心血管风险因素管理,对于降低LEA率和改善结果至关重要.
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