作为IgG4相关疾病的不同寻常的初始表现:一种诊断挑战
Parinya Ruenwilai1, Sarawut Kongkarnka2, Athitarn Tangtermpong3
1Division of Pulmonary, Critical Care and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, THA.
Cureus
|September 29, 2025
概括
一名79岁的男性患有渐进性呼吸障碍,被诊断出患有IgG4相关疾病 (IgG4-RD),呈现为异氨酸性多流液. 用皮质类固醇治疗导致出血完全消失.
科学领域:
- 肺部病理学 肺部病理学
- 类风湿病学 类风湿病学
- 病理学 病理学 病理学
背景情况:
- 胸腔溢出可以呈现出各种不同的病因.
- 与IgG4相关的疾病 (IgG4-RD) 是一种多系统纤维炎症疾病.
- 乙酸性多流是不常见的,需要彻底调查.
研究的目的:
- 报告一种罕见的IgG4相关疾病病例,呈现为异氨酸性多流液.
- 突出诊断挑战和成功管理这种情况.
主要方法:
- 一个79岁的男性患有呼吸障碍的案例介绍.
- 诊断工作包括胸部X射线图,胸腔液分析,医学胸腔镜和胸腔活检.
- 组织病理学检查,以确认IgG4相关的疾病.
主要成果:
- 观察到渐进性呼吸不全和左侧的多发性溢出.
- 胸腔液分析显示,表皮液的表皮形状与埃索诺菲尔细胞有关.
- 医学胸腔镜检查显示有过色素的多叶膜斑.
- 组织病理学证实了IgG4相关的疾病.
结论:
- 与IgG4相关的疾病可以表现为一种eosinophilic 膜溢出.
- 通过组织病理学早期诊断至关重要.
- 皮质类固醇治疗在治疗IgG4-RD相关的多流液方面是有效的.
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