通过工作道进行内支气管超声波引导的横支气管冷活检,有可能提高安全性和疗效
Mikito Suzuki1, Kaito Yano1, Tomohiro Imoto1
1Department of Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22 Honkomagome, Bunkyo-ku, Tokyo, 113-8677, Japan.
Respiratory medicine case reports
|September 29, 2025
概括
一种新的内支气管超声波 (EBUS) 引导的跨支气管冷活检 (TBCB) 方法允许直接采集样本. 这种技术提高了诊断状和中状病变的安全性和效率.
科学领域:
- 肺部病理学 肺部病理学
- 干预性肺病学 干预性肺病学
- 医疗器械 医疗器械
背景情况:
- 内支气管超声波 (EBUS) 引导的横支气管冷藏活检 (TBCB) 用于诊断状和中支气管病变.
- 传统的TBCB有风险,包括延迟部位观察,静血应用和潜在的出血.
- 由于重新识别病变,重复的冷探针通过可能会耗费大量时间.
研究的目的:
- 在EBUS-TBCB期间引入一种用于直接采样的新方法.
- 提高EBUS-TBCB程序的安全性和效率.
- 为了能够立即进行活检后部位评估和血液静止.
主要方法:
- 开发了一种新的EBUS-TBCB技术,涉及通过工作道直接采集样本.
- 手术是在局部麻醉下进行的,没有输管.
- 通过穿孔通道将冷探针引入病变中,在4秒的冷时间后收集样本.
主要成果:
- 这种新方法允许通过工作道直接采集样本.
- 保留EBUS范围使即时可视化和静血应用成为可能.
- 在两个案例中,使用3-4个样本实现了最终诊断,过程时间短 (2.2分钟和3.0分钟).
- 在这两种情况下,只观察到轻度出血.
结论:
- 新的直接采集方法提高了EBUS-TBCB的安全性,即使没有输管.
- 这种技术简化了活检过程,减少了手术时间,提高了诊断产量.
- 它提供了一种更安全的替代方案,用于从中骨和骨病变中获取组织样本.
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