阻塞性睡眠呼吸暂停中的炎症:全球图书识别视角
Haixia Fan1, Huiyan Niu2, Bomeng Zhao2
1Department of Sleep Center, First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, People's Republic of China.
Nature and science of sleep
|September 29, 2025
概括
本文库分析绘制了全球关于阻塞性睡眠呼吸暂停 (OSA) 炎症的研究,揭示了关键的贡献者和趋势. 未来的研究应该专注于生物标志物和抗炎疗法,以改善患者的治疗结果.
科学领域:
- 图书统计学 图书统计学
- 睡眠医学 睡眠医学
- 免疫学 免疫学 免疫学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 越来越被认为是一种全身性疾病.
- 炎症在OSA病理生理学和并发症中起着关键作用.
研究的目的:
- 进行首次对OSA炎症的全球研究进行全面的图书统计分析.
- 地图知识结构,识别有影响力的贡献者,并突出新兴研究趋势.
主要方法:
- 从网络科学核心集合 (1996-2025) 获取了关于OSA和炎症的出版物.
- 使用文献计量工具 (CiteSpace,VOSviewer,文献计量R包) 分析了2075篇文章和评论.
- 研究了引用频率,共同引用网络和协作模式.
主要成果:
- 出版物年增长率为12.11%,其中中国和美国是主要贡献者.
- 确定了关键机构 (哈佛大学,芝加哥大学,INSERM) 和作者 (Gozal D,Kheirandish-Gozal L,Khalyfa A).
- 突出的研究重点是心血管疾病,代谢综合征,神经炎症和治疗 (CPAP,手术);新兴主题包括肠道微生物群和维生素D.
结论:
- 关于OSA炎症的研究正在向临床管理和跨学科探索发展.
- 未来的优先事项包括生物标志物发现和抗炎治疗策略.
- 研究结果为有针对性的研究和临床转化提供了路线图,以改善患者的治疗结果.
相关概念视频
Sleep Apnea
481
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
481
Other Pulmonary Disorders
1.5K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
1.5K
Tonsillitis I: Introduction
1.8K
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
1.8K
Chronic Obstructive Pulmonary Disease-I: Introduction
3.6K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.6K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
4.2K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
4.2K
Chronic Obstructive Pulmonary Disease
2.3K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.3K


