对肺外结核患者临床,组织病理和放射特征的评估
Ladan Kharraz1,2, Aida Bagheri1, Firouze Hatami1,2
1Infectious Diseases and Tropical Medicine, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
肺外结核 (EPTB) 是多种多样的,结核性脑膜炎是最常见的. 肠道和介肠结核病的死亡率较高,可能是由于诊断延迟,诊断测试的阳性率较低.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 结核病 (TB) 呈现为肺 (PTB) 或肺外 (EPTB).
- 由于各种表现和医疗保健设置的局限性,EPTB诊断可能具有挑战性.
- 本综述侧重于EPTB病例在转诊中心.
研究的目的:
- 审查所有在转诊中心管理的肺外结核病例.
- 分析EPTB患者的临床特征,诊断挑战和结果.
主要方法:
- 十年来确认的EPTB病例的回顾性审查.
- 对患者人口统计,结核病部位,诊断测试结果和死亡率的分析.
主要成果:
- 分析了68例EPTB病例,58.8%的男性,41.2%的女性.
- 结核病脑膜炎是最常见的EPTB (44.1%),其次是肌肉骨结核病 (17.6%).
- 死亡率为19.1%,肠道/介质结核病的死亡率最高 (33.3%);涂抹/培养阳性低 (8.8%-19.1%).
结论:
- 结核病脑膜炎是住院EPTB的主要形式.
- 在肠道/介质结核病中死亡率较高表明诊断延迟.
- 涂抹和培养试验的低敏感性需要改善EPTB的诊断策略.
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