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Updated: Jan 16, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
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一项基于拼接的关节转录组多组织关联研究确定了骨关节炎易感基因

Lantao Zhang1, Fuxing Zhao2, Hengheng Zhang2

  • 1Department of Bone and Joint Surgery, Affiliated Hospital of Qinghai University, Xining, China.

Frontiers in immunology
|September 29, 2025
PubMed
概括

这项研究确定了潜伏转化生长因子β结合蛋白1 (LTBP1) 作为骨关节炎 (OA) 发病的关键基因. LTBP1调节状细胞的分化和信号通路,为OA的遗传基础提供了新的见解.

关键词:
一个LTBP1一个LTBP1遗传易感性是一种基因易感性.骨关节炎是一种关节炎.一个单细胞测序.转录组协会研究研究

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