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Updated: Apr 29, 2026

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眼科中细胞治疗系统的3D生物打印:从生物工程组织到个性化药物输送

Hyeonji Kim1, Gia-Han Ngo1,2, Wen Hong1

  • 1Department of Ophthalmology, School of Medicine, Byers Eye Institute at Stanford University, Palo Alto, CA 94304 USA.

Current ophthalmology reports
|September 29, 2025
PubMed
概括

三维 (3D) 生物打印为眼科细胞治疗提供了先进的细胞输送系统,克服了治疗眼病传统方法的局限性,并推动了再生医学的发展.

关键词:
3D生物打印技术的使用.细胞疗法是一种细胞疗法.药物输送是药物输送的过程.再生医学是一种再生医学.组织工程是组织工程.

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Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
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